Five year impact of chemotherapy on morbidity attributable to Schistosoma japonicum infection in the Dongting Lake region.

Détails

ID Serval
serval:BIB_7320
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Five year impact of chemotherapy on morbidity attributable to Schistosoma japonicum infection in the Dongting Lake region.
Périodique
Tropical Medicine and International Health
Auteur(s)
Ross A.G., Li Y., Booth M., Sleigh A.C., Williams G.M., McManus D.P.
ISSN
1360-2276
Statut éditorial
Publié
Date de publication
1998
Volume
3
Numéro
10
Pages
837-841
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Résumé
OBJECTIVE: To determine changes in the last 5 years of the fraction of acute and chronic symptoms attributable to schistosomiasis japonica in fishing communities with moderate endemicity in the Dongting Lake region of China. METHOD: Complete medical histories, physical examinations, and stool samples were obtained from 1909 individuals (53% male) ranging in age from 4 to 81 years. Age, sex, occupation, frequency of water contact, number of times treated for schistosomiasis, and last year of treatment were tested as potential effect modifiers and confounders. RESULTS: Overall, there were very few infected cases and very little variation in any prevalence ratio with infection intensity, sex, age, year of last treatment, number of times treated or frequency of water contact. The attributable fraction of liver enlargement in one village was estimated at 0.114 (11.4%), although this was not significantly > 0(95% CI; -0.008-0.237). CONCLUSION: The chemotherapy-based schistosomiasis control programme in this locality has succeeded in reducing attributable morbidity to undetectable levels, but many uncertainties remain about sustaining control efforts in the future. Both old and new control strategies will have to be examined if the health and well-being of these people are to be maintained into the next millennium, given that periodic chemotherapy will not be accepted indefinitely.
Mots-clé
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, China/epidemiology, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Schistosomiasis japonica/drug therapy, Schistosomiasis japonica/epidemiology
Pubmed
Web of science
Création de la notice
19/11/2007 13:45
Dernière modification de la notice
03/03/2018 18:18
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