Phantom Validation of Tc-99m Absolute Quantification in a SPECT/CT Commercial Device.

Détails

Ressource 1Télécharger: 28096891_BIB_72FD3CCBBBFC.pdf (1363.22 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_72FD3CCBBBFC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Phantom Validation of Tc-99m Absolute Quantification in a SPECT/CT Commercial Device.
Périodique
Computational and mathematical methods in medicine
Auteur(s)
Gnesin S., Leite Ferreira P., Malterre J., Laub P., Prior J.O., Verdun F.R.
ISSN
1748-6718 (Electronic)
ISSN-L
1748-670X
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
2016
Pages
4360371
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Aim. Similar to PET, absolute quantitative imaging is becoming available in commercial SPECT/CT devices. This study's goal was to assess quantitative accuracy of activity recovery as a function of image reconstruction parameters and count statistics in a variety of phantoms. Materials and Methods. We performed quantitative (99m)Tc-SPECT/CT acquisitions (Siemens Symbia Intevo, Erlangen, Germany) of a uniform cylindrical, NEMA/IEC, and an anthropomorphic abdominal phantom. Background activity concentrations tested ranged: 2-80 kBq/mL. SPECT acquisitions used 120 projections (20 s/projection). Reconstructions were performed with the proprietary iterative conjugate gradient algorithm. NEMA phantom reconstructions were obtained as a function of the iteration number (range: 4-48). Recovery coefficients, hot contrast, relative lung error (NEMA phantom), and image noise were assessed. Results. In all cases, absolute activity and activity concentration were measured within 10% of the expected value. Recovery coefficients and hot contrast in hot inserts did not vary appreciably with count statistics. RC converged at 16 iterations for insert size > 22 mm. Relative lung errors were comparable to PET levels indicating the efficient integration of attenuation and scatter corrections with adequate detector modeling. Conclusions. The tested device provided accurate activity recovery within 10% of correct values; these performances are comparable to current generation PET/CT systems.

Mots-clé
Abdomen/physiopathology, Algorithms, Anthropometry, Humans, Image Processing, Computer-Assisted/methods, Lung/diagnostic imaging, Lung/pathology, Normal Distribution, Phantoms, Imaging, Positron-Emission Tomography, Radiometry/methods, Reproducibility of Results, Single Photon Emission Computed Tomography Computed Tomography/instrumentation, Single Photon Emission Computed Tomography Computed Tomography/methods, Technetium/chemistry
Pubmed
Open Access
Oui
Création de la notice
19/01/2017 17:37
Dernière modification de la notice
08/05/2019 20:23
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