New look at endometrial echogenicity: objective computer-assisted measurements predict endometrial receptivity in in vitro fertilization-embryo transfer

Détails

ID Serval
serval:BIB_72C9D77DDBA3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
New look at endometrial echogenicity: objective computer-assisted measurements predict endometrial receptivity in in vitro fertilization-embryo transfer
Périodique
Fertility and Sterility
Auteur(s)
Fanchin  R., Righini  C., Ayoubi  J. M., Olivennes  F., de Ziegler  D., Frydman  R.
ISSN
0015-0282
Statut éditorial
Publié
Date de publication
08/2000
Peer-reviewed
Oui
Volume
74
Numéro
2
Pages
274-81
Notes
Journal Article --- Old month value: Aug
Résumé
OBJECTIVE: To determine whether endometrial echogenicity, assessed objectively by a computer-assisted system on the day of hCG administration, predicts endometrial receptivity in controlled ovarian hyperstimulation (COH) cycles for IVF-ET. DESIGN: Prospective analysis. SETTING: Assisted reproduction unit, Clamart, France. PATIENT(S): Two hundred twenty-one women (aged <38 years with a normal uterus and >/=2 grade A or B embryos transferred) undergoing 228 GnRH agonist and FSH/hCG cycles for IVF-ET. INTERVENTION(S): On the day of hCG administration, uterine ultrasound scans were digitized with an image analysis system. Endometrial echogenicity was assessed as the ratio of the extent of the hyperechogenic transformation over the whole endometrial thickness. According to this, cycles were sorted arbitrarily into six groups: <30% (n = 34), 31%-40% (n = 37), 41%-50% (n = 37), 51%-60% (n = 55), 61%-70% (n = 37), and >70% (n = 28). MAIN OUTCOME MEASURE(S): Pregnancy and implantation rates. RESULT(S): The groups were similar in regard to population characteristics, ovarian response to COH, and embryology data. Pregnancy rates (59%, 57%, 35%, 20%, 16%, and 11%, respectively) and implantation rates (35%, 23%, 17%, 6%, 7%, and 3%, respectively) fell progressively and significantly from the low-echogenicity group to the high-echogenicity group. CONCLUSION(S): The present results confirm and extend previous observations that advanced hyperechogenic transformation of the endometrium is associated with poor IVF-ET outcome.
Mots-clé
Adult Chorionic Gonadotropin/therapeutic use Embryo Implantation *Embryo Transfer Endometrium/*physiology/*ultrasonography Female *Fertilization in Vitro Humans Image Processing, Computer-Assisted/*methods Ovary/drug effects/physiology Pregnancy Pregnancy Rate Prospective Studies
Pubmed
Web of science
Création de la notice
28/02/2008 12:37
Dernière modification de la notice
03/03/2018 18:18
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