Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_72274CF26633
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy.
Périodique
Oncotarget
Auteur(s)
Blagodatski A., Yatsunskaya M., Mikhailova V., Tiasto V., Kagansky A., Katanaev V.L.
ISSN
1949-2553 (Electronic)
ISSN-L
1949-2553
Statut éditorial
Publié
Date de publication
26/06/2018
Peer-reviewed
Oui
Volume
9
Numéro
49
Pages
29259-29274
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Medicinal mushrooms have been used throughout the history of mankind for treatment of various diseases including cancer. Nowadays they have been intensively studied in order to reveal the chemical nature and mechanisms of action of their biomedical capacity. Targeted treatment of cancer, non-harmful for healthy tissues, has become a desired goal in recent decades and compounds of fungal origin provide a vast reservoir of potential innovational drugs. Here, on example of four mushrooms common for use in Asian and Far Eastern folk medicine we demonstrate the complex and multilevel nature of their anticancer potential, basing upon different groups of compounds that can simultaneously target diverse biological processes relevant for cancer treatment, focusing on targeted approaches specific to malignant tissues. We show that some aspects of fungotherapy of tumors are studied relatively well, while others are still waiting to be fully unraveled. We also pay attention to the cancer types that are especially susceptible to the fungal treatments.
Mots-clé
biomedicine, cancer, fungotherapy, medicinal mushrooms, targeted treatment
Pubmed
Open Access
Oui
Création de la notice
06/08/2018 16:11
Dernière modification de la notice
21/08/2019 6:09
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