Octogenarians with uncomplicated acute type a aortic dissection benefit from emergency operation.
Details
Serval ID
serval:BIB_7105C0D38C0B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Octogenarians with uncomplicated acute type a aortic dissection benefit from emergency operation.
Journal
The Annals of thoracic surgery
ISSN
1552-6259 (Electronic)
ISSN-L
0003-4975
Publication state
Published
Issued date
09/2013
Peer-reviewed
Oui
Volume
96
Number
3
Pages
851-856
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The management of acute type A aortic dissection (aTAAD) in octogenarian patients is controversial. This study analyzed the surgical outcomes to identify patients who should undergo operations.
Beginning in January 2000, we established a registry including all octogenarian patients operated on for type A acute aortic dissection. We evaluated 79 consecutive patients enrolled up to December 2010. Their median age was 81.6 years (range, 80 to 89 years). Sixteen patients (20%) presented a complicated type because of a neurologic deficit, mesenteric ischemia, a requirement for cardiopulmonary resuscitation, or some combination of those features. Operations followed the standard procedure recommended for younger patients. Follow-up was 95% complete (mean, 4.6±2.8 years).
The overall in-hospital mortality was 44.3%. The in-hospital mortality among patients with uncomplicated aTAAD was 33.3%. Multivariate analysis identified complicated aTAAD as the only risk factors for in-hospital mortality (p<0.0001). Postoperative complications occurred in 50 patients (68.5%) and were associated with a higher mortality (p<0.0001). The overall survival was 53% at 1 year and 32% at 5 years. In uncomplicated aTAAD, the overall survival was 63% at 1 year and 38% at 5 years.
Octogenarians with uncomplicated aTAAD benefit from emergency surgical repair. In those patients, early and midterm outcomes are good and are similar to those in published series of younger patients. Complicated aTAAD should be medically managed.
Beginning in January 2000, we established a registry including all octogenarian patients operated on for type A acute aortic dissection. We evaluated 79 consecutive patients enrolled up to December 2010. Their median age was 81.6 years (range, 80 to 89 years). Sixteen patients (20%) presented a complicated type because of a neurologic deficit, mesenteric ischemia, a requirement for cardiopulmonary resuscitation, or some combination of those features. Operations followed the standard procedure recommended for younger patients. Follow-up was 95% complete (mean, 4.6±2.8 years).
The overall in-hospital mortality was 44.3%. The in-hospital mortality among patients with uncomplicated aTAAD was 33.3%. Multivariate analysis identified complicated aTAAD as the only risk factors for in-hospital mortality (p<0.0001). Postoperative complications occurred in 50 patients (68.5%) and were associated with a higher mortality (p<0.0001). The overall survival was 53% at 1 year and 32% at 5 years. In uncomplicated aTAAD, the overall survival was 63% at 1 year and 38% at 5 years.
Octogenarians with uncomplicated aTAAD benefit from emergency surgical repair. In those patients, early and midterm outcomes are good and are similar to those in published series of younger patients. Complicated aTAAD should be medically managed.
Keywords
Acute Disease, Aged, 80 and over, Analysis of Variance, Aneurysm, Dissecting/diagnostic imaging, Aneurysm, Dissecting/mortality, Aneurysm, Dissecting/surgery, Aortic Aneurysm, Thoracic/diagnostic imaging, Aortic Aneurysm, Thoracic/mortality, Aortic Aneurysm, Thoracic/surgery, Blood Vessel Prosthesis Implantation/methods, Blood Vessel Prosthesis Implantation/mortality, Emergencies, Female, Follow-Up Studies, Geriatric Assessment, Hospital Mortality/trends, Humans, Male, Multivariate Analysis, Postoperative Complications/mortality, Postoperative Complications/physiopathology, Registries, Retrospective Studies, Risk Assessment, Survival Rate, Survivors/statistics & numerical data, Time Factors, Treatment Outcome, Ultrasonography, 26
Pubmed
Web of science
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28/03/2019 17:41
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