Pathogenesis of Cardiovascular and Metabolic Diseases: Are Fructose-Containing Sugars More Involved Than Other Dietary Calories?
Details
Download: BIB_6EEEAE1058BA.P001.pdf (1026.39 [Ko])
State: Public
Version: Final published version
State: Public
Version: Final published version
Serval ID
serval:BIB_6EEEAE1058BA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Pathogenesis of Cardiovascular and Metabolic Diseases: Are Fructose-Containing Sugars More Involved Than Other Dietary Calories?
Journal
Current hypertension reports
ISSN
1534-3111 (Electronic)
ISSN-L
1522-6417
Publication state
Published
Issued date
06/2016
Peer-reviewed
Oui
Volume
18
Number
6
Pages
44
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
There is increasing concern that sugar consumption may be linked to the development of metabolic and cardiovascular diseases. There is indeed strong evidence that consumption of energy-dense sugary beverages and foods is associated with increased energy intake and body weight gain over time. It is further proposed that the fructose component of sugars may exert specific deleterious effects due to its propension to stimulate hepatic glucose production and de novo lipogenesis. Excess fructose and energy intake may be associated with visceral obesity, intrahepatic fat accumulation, and high fasting and postprandial blood triglyceride concentrations. Additional effects of fructose on blood uric acid and sympathetic nervous system activity have also been reported, but their link with metabolic and cardiovascular diseases remains hypothetical. There is growing evidence that fructose at physiologically consumed doses may exert important effects on kidney function. Whether this is related to the development of high blood pressure and cardiovascular diseases remains to be further assessed.
Keywords
Cardiovascular Diseases/metabolism, Cardiovascular Diseases/physiopathology, Energy Intake/physiology, Fructose/metabolism, Glucose/metabolism, Humans, Lipogenesis/physiology, Metabolic Diseases/metabolism, Metabolic Diseases/physiopathology, Risk Factors
Pubmed
Open Access
Yes
Create date
05/05/2016 11:32
Last modification date
20/08/2019 14:28