Respiratory effects of an exposure to grain dust among grain workers in the Vaud region (Switzerland)

Détails

ID Serval
serval:BIB_6E8506F84FE9
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Titre
Respiratory effects of an exposure to grain dust among grain workers in the Vaud region (Switzerland)
Titre de la conférence
ERS 23rd Annual Congress, Barcelona Spain, 7-11 September 2013
Auteur(s)
Dorribo Victor, Pralong Jacques A., Wild Pascal, Reboux Gabriel, Oppliger Anne, Danuser Brigitta, Niculita-Hirzel Hélène, Krief Peggy
ISSN-L
1399-3003
Statut éditorial
Publié
Date de publication
2013
Volume
42
Série
European Respiratory Journal
Pages
201s-202s
Langue
anglais
Résumé
Introduction: Bioaerosols such as grain dust (GD) elicit direct immunological reactions within the human respiratory system. Workplace-dependent exposure to GD may induce asthma, chronic bronchitis, and hypersensitivity pneumonitis.
Aims: To assess the clinical impact of occupational exposure to GD and to determine quantitative biological markers of bioaerosol exposure in grain workers.
Methods: This longitudinal study has been conducted from summer 2012 to summer 2013, comprising 6 groups of 30 active workers with different GD exposure patterns (4 groups of grain workers, 2 control groups). Two evaluations at high- and low-exposing seasons take place, during which an occupational and a medical history are questionnaire-assessed, lung function is evaluated by spirometry, airway inflammation is measured by exhaled nitric oxide (eNO) and specific blood IgG and IgE are titrated.
Results: The preliminary results are those of 2 of the 4 exposed groups, (harvesters and mill workers), compared to the control groups, at first assessment (n=100). Mean age is 38.4 [years]; 98% are male. Exposed groups differ from controls (p<0.05) in daily contact with animals (57% vs. 40%) and active smoking (39% vs. 11%). Grain workers have more respiratory (50%), nasal (57%), ocular (45%) and dermatologic (36%) occupational symptoms than controls (6.4%, 19%, 16%, 6.4% respectively, p<0.05). Lower mean peak-expiratory-flow (PEF) values (96.1 ± 18.9 vs. 108.2 ± 17.4 [% of predicted], p<0.05) and eNO values (13.9 ± 9.6 vs. 20.5 ± 14.7 [ppm], p<0.05) are observed in the exposed groups.
Conclusion: Preliminary results show a higher prevalence of clinical symptoms and a lower mean PEF value in the groups exposed to GD.
Mots-clé
Occupational Exposure, Endotoxins/analysis, Agricultural Workers' Diseases/prevention & control, Switzerland
Création de la notice
15/10/2013 16:15
Dernière modification de la notice
20/08/2019 15:27
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