Clinical features of myocardial infarction and myocarditis in young adults: a retrospective study.

Détails

Ressource 1Télécharger: BIB_6D2166FAAA21.P001.pdf (212.96 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_6D2166FAAA21
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Clinical features of myocardial infarction and myocarditis in young adults: a retrospective study.
Périodique
BMJ Open
Auteur(s)
Pellaton C., Monney P., Ludman A.J., Schwitter J., Eeckhout E., Hugli O., Muller O.
ISSN
2044-6055 (Electronic)
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
2
Numéro
6
Pages
1-6
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: epublish. PDF type: Research
Résumé
OBJECTIVES: To evaluate the prevalence and clinical presentation of myocardial infarction (MI) and myocarditis in young adults presenting with chest pain (CP) and an elevated serum troponin I (TnI) to the emergency department (ED).
DESIGN: Retrospective, observational, single-centre study.
PARTICIPANTS: All consecutive patients 18-40 years old admitted to the ED for CP with an elevated TnI concentration.
PRIMARY OUTCOME MEASURES: Prevalence of MI, myocarditis and the characterisation of clinical presentation.
RESULTS: 1588 patients between 18 and 40 years old were admitted to the ED with CP during 30 consecutive months. 49 (3.1%) patients with an elevated TnI (>0.09 μg/l) were included. 32.7% (16/49) were diagnosed with MI (11 ST-elevation myocardial infarction (STEMI) and 5 non-ST-elevation myocardial infarction (NSTEMI)) and 59.2% (29/49) with myocarditis. Compared with patients with myocarditis, MI patients were older (34.1±3.8 vs 26.9±6.4, p=0.0002) with more cardiovascular risk factors (mean 2.06 vs 0.69). Diabetes (18.8% vs 0%, p=0.0039), dyslipidaemia (56.2% vs 3.4%, p<0.0001) and family history of coronary artery disease (CAD) (37.5% vs 10.3% p=0.050) were associated with MI. Fever or recent viral illness were present in 75.9% (22/29) of patients with myocarditis, and in 0% of MI patients (p<0.0001). During follow-up, two patients with myocarditis were re-admitted for CP.
CONCLUSIONS: In this study, 32.7% of patients <40-year-old admitted to an ED with CP and elevated TnI had a diagnosis of MI. Key distinctive clinical factors include diabetes, dyslipidaemia, family history of CAD and fever or recent viral illness.
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/02/2013 11:33
Dernière modification de la notice
20/08/2019 15:26
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