Mouse alarm pheromone shares structural similarity with predator scents.

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Etat: Serval
Version: Final published version
ID Serval
serval:BIB_6BBC271BEB2F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Mouse alarm pheromone shares structural similarity with predator scents.
Périodique
Proceedings of the National Academy of Sciences of the United States of America
Auteur(s)
Brechbühl J., Moine F., Klaey M., Nenniger-Tosato M., Hurni N., Sporkert F., Giroud C., Broillet M.C.
ISSN
1091-6490 (Electronic)
ISSN-L
0027-8424
Statut éditorial
Publié
Date de publication
2013
Volume
110
Numéro
12
Pages
4762-4767
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
Sensing the chemical warnings present in the environment is essential for species survival. In mammals, this form of danger communication occurs via the release of natural predator scents that can involuntarily warn the prey or by the production of alarm pheromones by the stressed prey alerting its conspecifics. Although we previously identified the olfactory Grueneberg ganglion as the sensory organ through which mammalian alarm pheromones signal a threatening situation, the chemical nature of these cues remains elusive. We here identify, through chemical analysis in combination with a series of physiological and behavioral tests, the chemical structure of a mouse alarm pheromone. To successfully recognize the volatile cues that signal danger, we based our selection on their activation of the mouse olfactory Grueneberg ganglion and the concomitant display of innate fear reactions. Interestingly, we found that the chemical structure of the identified mouse alarm pheromone has similar features as the sulfur-containing volatiles that are released by predating carnivores. Our findings thus not only reveal a chemical Leitmotiv that underlies signaling of fear, but also point to a double role for the olfactory Grueneberg ganglion in intraspecies as well as interspecies communication of danger.
Mots-clé
Olfaction, Animal communication, Behavior, Calcium imaging
Pubmed
Web of science
Open Access
Oui
Création de la notice
22/03/2013 16:14
Dernière modification de la notice
08/05/2019 20:00
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