A mechanosensory receptor required for food texture detection in Drosophila.

Détails

Ressource 1Télécharger: ncomms14192.pdf (4193.27 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_6B556BB61EE2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
A mechanosensory receptor required for food texture detection in Drosophila.
Périodique
Nature communications
Auteur(s)
Sánchez-Alcañiz J.A., Zappia G., Marion-Poll F., Benton R.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Statut éditorial
Publié
Date de publication
27/01/2017
Peer-reviewed
Oui
Volume
8
Pages
14192
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
Textural properties provide information on the ingestibility, digestibility and state of ripeness or decay of sources of nutrition. Compared with our understanding of the chemosensory assessment of food, little is known about the mechanisms of texture detection. Here we show that Drosophila melanogaster can discriminate food texture, avoiding substrates that are either too hard or too soft. Manipulations of food substrate properties and flies' chemosensory inputs indicate that texture preferences are revealed only in the presence of an appetitive stimulus, but are not because of changes in nutrient accessibility, suggesting that animals discriminate the substrates' mechanical characteristics. We show that texture preference requires NOMPC, a TRP-family mechanosensory channel. NOMPC localizes to the sensory dendrites of neurons housed within gustatory sensilla, and is essential for their mechanosensory-evoked responses. Our results identify a sensory pathway for texture detection and reveal the behavioural integration of chemical and physical qualities of food.
Mots-clé
Animals, Animals, Genetically Modified, Dendrites/physiology, Drosophila Proteins/physiology, Drosophila melanogaster/physiology, Eating/physiology, Feeding Behavior/physiology, Male, Mechanoreceptors/physiology, Mechanotransduction, Cellular/physiology, Sensilla/cytology, Sensilla/physiology, Transient Receptor Potential Channels/physiology
Pubmed
Open Access
Oui
Création de la notice
07/02/2017 19:34
Dernière modification de la notice
20/08/2019 15:25
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