A mechanosensory receptor required for food texture detection in Drosophila.

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State: Public
Version: Final published version
Serval ID
serval:BIB_6B556BB61EE2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A mechanosensory receptor required for food texture detection in Drosophila.
Journal
Nature communications
Author(s)
Sánchez-Alcañiz J.A., Zappia G., Marion-Poll F., Benton R.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
27/01/2017
Peer-reviewed
Oui
Volume
8
Pages
14192
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Textural properties provide information on the ingestibility, digestibility and state of ripeness or decay of sources of nutrition. Compared with our understanding of the chemosensory assessment of food, little is known about the mechanisms of texture detection. Here we show that Drosophila melanogaster can discriminate food texture, avoiding substrates that are either too hard or too soft. Manipulations of food substrate properties and flies' chemosensory inputs indicate that texture preferences are revealed only in the presence of an appetitive stimulus, but are not because of changes in nutrient accessibility, suggesting that animals discriminate the substrates' mechanical characteristics. We show that texture preference requires NOMPC, a TRP-family mechanosensory channel. NOMPC localizes to the sensory dendrites of neurons housed within gustatory sensilla, and is essential for their mechanosensory-evoked responses. Our results identify a sensory pathway for texture detection and reveal the behavioural integration of chemical and physical qualities of food.
Keywords
Animals, Animals, Genetically Modified, Dendrites/physiology, Drosophila Proteins/physiology, Drosophila melanogaster/physiology, Eating/physiology, Feeding Behavior/physiology, Male, Mechanoreceptors/physiology, Mechanotransduction, Cellular/physiology, Sensilla/cytology, Sensilla/physiology, Transient Receptor Potential Channels/physiology
Pubmed
Open Access
Yes
Create date
07/02/2017 18:34
Last modification date
21/11/2022 8:22
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