Circulating sodium in acute meningitis
Details
Serval ID
serval:BIB_6AE76293328C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Circulating sodium in acute meningitis
Journal
American Journal of Nephrology
ISSN
0250-8095 (Print)
Publication state
Published
Issued date
04/2001
Volume
21
Number
2
Pages
87-90
Notes
Journal Article --- Old month value: Mar-Apr
Abstract
BACKGROUND: In acute meningitis hyponatremia is common and traditionally attributed exclusively to inappropriate water retention. However, the exact mechanisms underlying hyponatremia are unknown. METHODS: The files of 300 pediatric patients with acute bacterial (n = 190) or aseptic (n = 110) meningitides were retrospectively analyzed. RESULTS: The plasma sodium level ranged from 122 to 148 mmol/l and was low (<133 mmol/l) in 97 patients. Fluid volume contraction was significantly more pronounced in hyponatremia (median 6.0. 10(-2)) than in normonatremia (median 2.0. 10(-2)). The fractional sodium excretion was less than 1.00. 10(-2) in the 26 hyponatremic children with this measurement. CONCLUSION: In acute meningitis hyponatremia is not exclusively brought about by inappropriate water retention.
Keywords
Acute Disease
Female
Humans
Hyponatremia/etiology
Infant
Infant, Newborn
Male
Meningitis/*blood/complications
Meningitis, Aseptic/blood/complications
Meningitis, Bacterial/blood/complications
Retrospective Studies
Sodium/*blood
Pubmed
Web of science
Create date
28/01/2008 14:50
Last modification date
20/08/2019 15:25