Article: article from journal or magazin.
Circulating sodium in acute meningitis
American Journal of Nephrology
Journal Article --- Old month value: Mar-Apr
BACKGROUND: In acute meningitis hyponatremia is common and traditionally attributed exclusively to inappropriate water retention. However, the exact mechanisms underlying hyponatremia are unknown. METHODS: The files of 300 pediatric patients with acute bacterial (n = 190) or aseptic (n = 110) meningitides were retrospectively analyzed. RESULTS: The plasma sodium level ranged from 122 to 148 mmol/l and was low (<133 mmol/l) in 97 patients. Fluid volume contraction was significantly more pronounced in hyponatremia (median 6.0. 10(-2)) than in normonatremia (median 2.0. 10(-2)). The fractional sodium excretion was less than 1.00. 10(-2) in the 26 hyponatremic children with this measurement. CONCLUSION: In acute meningitis hyponatremia is not exclusively brought about by inappropriate water retention.
Acute Disease Female Humans Hyponatremia/etiology Infant Infant, Newborn Male Meningitis/*blood/complications Meningitis, Aseptic/blood/complications Meningitis, Bacterial/blood/complications Retrospective Studies Sodium/*blood
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