Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney.
Details
Download: 38910347.pdf (4139.20 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0
State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_6A48E2F7305E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney.
Journal
Blood pressure
ISSN
1651-1999 (Electronic)
ISSN-L
0803-7051
Publication state
Published
Issued date
12/2024
Peer-reviewed
Oui
Volume
33
Number
1
Pages
2368800
Language
english
Notes
Publication types: Journal Article ; Multicenter Study
Publication Status: ppublish
Publication Status: ppublish
Abstract
Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representatives from 27 countries participated. According to the responders, renin-angiotensin system (RAS) blockers, calcium-channel blockers and thiazides were often added when these medications were lacking in CKD patients, but physicians were more prone to initiate RAS blockers (90% [interquartile range: 70-95%]) than MRA (20% [10-30%]), SGLT2i (30% [20-50%]) or (GLP1-RA (10% [5-15%]). Despite treatment optimisation, 30% of responders indicated that hypertension remained uncontrolled (30% (15-40%) vs 18% [10%-25%]) in CKD and CKD patients, respectively). Hyperkalemia was the most frequent barrier to initiate RAS blockers, and dosage reduction was considered in 45% of responders when kalaemia was 5.5-5.9 mmol/L. Conclusions RAS blockers are initiated in most ESH-ECS in CKD patients, but MRA and SGLT2i initiations are less frequent. Hyperkalemia was the main barrier for initiation or adequate dosing of RAS blockade, and RAS blockers' dosage reduction was the usual management.
Keywords
Humans, Renal Insufficiency, Chronic/complications, Renal Insufficiency, Chronic/drug therapy, Hypertension/drug therapy, Europe, Antihypertensive Agents/therapeutic use, Male, Surveys and Questionnaires, Female, Middle Aged, Calcium Channel Blockers/therapeutic use, Societies, Medical, Angiotensin Receptor Antagonists/therapeutic use, Chronic kidney disease, RAS blockers, SGLT2 inhibitors, guidelines, hyperkalaemia, hypertension, management, mineralocorticoid receptor antagonists
Pubmed
Open Access
Yes
Create date
28/06/2024 11:27
Last modification date
29/06/2024 8:54