Prevalence and clinical significance of incidental F18-FDG breast uptake: a systematic review and meta-analysis.

Détails

ID Serval
serval:BIB_69DDFFDD6AEE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Prevalence and clinical significance of incidental F18-FDG breast uptake: a systematic review and meta-analysis.
Périodique
Japanese journal of radiology
Auteur(s)
Bertagna F., Treglia G., Orlando E., Dognini L., Giovanella L., Sadeghi R., Giubbini R.
ISSN
1867-108X (Electronic)
ISSN-L
1867-1071
Statut éditorial
Publié
Date de publication
02/2014
Peer-reviewed
Oui
Volume
32
Numéro
2
Pages
59-68
Langue
anglais
Notes
Publication types: Journal Article ; Meta-Analysis ; Review
Publication Status: ppublish
Résumé
This review aims to analyse the published data on the prevalence and clinical significance of breast incidental F18-FDG uptake detected by PET or PET/CT (BIU). A comprehensive computer literature search of the PubMed/MEDLINE, Scopus and Embase databases for studies on BIU published through July 2013 was performed. Pooled prevalence and malignancy risk of BIU were calculated. The literature search revealed 42 articles, and 17 were selected. One study was excluded because of data overlap but four additional studies were found screening the references. Finally, 20 articles were included in the systematic review and 13 were eligible for a meta-analysis. The pooled prevalence of BIU on all scans was 0.4 % (95 % CI 0.23-0.61 %), the pooled prevalence on scans on female patients only was 0.82 % (95 % CI 0.51-1.2 %), the pooled risk of malignancy of BIU when further analysed was 48 % (95 % CI 38-58 %) and the pooled risk of malignancy of BIU with histological examination was 60 % (95 % CI 53-66 %). The most frequent malignant lesion detected was infiltrating ductal carcinoma. Despite being rare, the identification of BIU frequently signals the presence of an unsuspected subclinical lesion, which differs from the indicated reason for which the patient was initially scanned, and the risk of malignancy is very high.

Mots-clé
Aged, Breast/diagnostic imaging, Breast Neoplasms/diagnostic imaging, Female, Fluorodeoxyglucose F18, Humans, Positron-Emission Tomography, Prevalence, Radiopharmaceuticals, Tomography, X-Ray Computed
Pubmed
Web of science
Création de la notice
20/08/2017 19:48
Dernière modification de la notice
03/03/2018 18:00
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