Language Regression Associated With Autistic Regression and Electroencephalographic (EEG) Abnormalities: A Prospective Study.

Détails

ID Serval
serval:BIB_694F71738CDF
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Language Regression Associated With Autistic Regression and Electroencephalographic (EEG) Abnormalities: A Prospective Study.
Périodique
Journal of Child Neurology
Auteur(s)
Chilosi A.M., Brovedani P., Ferrari A.R., Ziegler A.L., Guerrini R., Deonna T.
ISSN
1708-8283 (Electronic)
ISSN-L
0883-0738
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
29
Numéro
6
Pages
855-859
Langue
anglais
Notes
Publication types: ARTICLE
Résumé
We report a boy, referred at 25 months following a dramatic isolated language regression antedating autistic-like symptomatology. His sleep electroencephalogram (EEG) showed persistent focal epileptiform activity over the left parietal and vertex areas never associated with clinical seizures. He was started on adrenocorticotropic hormone (ACTH) with a significant improvement in language, behavior, and in EEG discharges in rapid eye movement (REM) sleep. Later course was characterized by fluctuations/regressions in language and behavior abilities, in phase with recrudescence of EEG abnormalities prompting additional ACTH courses that led to remarkable decrease in EEG abnormalities, improvement in language, and to a lesser degree, in autistic behavior. The timely documentation of regression episodes suggesting an "atypical" autistic regression, striking therapy-induced improvement, fluctuation of symptomatology over time could be ascribed to recurrent and persisting EEG abnormalities.
Pubmed
Web of science
Création de la notice
05/09/2014 18:20
Dernière modification de la notice
20/08/2019 15:24
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