Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Phenotypic variation in bacteria: the role of feedback regulation.
Nature Reviews. Microbiology
To survive in rapidly changing environmental conditions, bacteria have evolved a diverse set of regulatory pathways that govern various adaptive responses. Recent research has reinforced the notion that bacteria use feedback-based circuitry to generate population heterogeneity in natural situations. Using artificial gene networks, it has been shown that a relatively simple 'wiring' of a bacterial genetic system can generate two or more stable subpopulations within an overall genetically homogeneous population. This review discusses the ubiquity of these processes throughout nature, as well as the presumed molecular mechanisms responsible for the heterogeneity observed in a selection of bacterial species.
Adaptation, Physiological, Bacteria/cytology, Bacteria/genetics, Feedback, Physiological/physiology, Gene Expression Regulation, Bacterial, Phenotype, Virulence/genetics
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