[Preventive relapse treatment for tobacco cessation - is it worthwhile?]

Details

Serval ID
serval:BIB_68858636AE86
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
[Preventive relapse treatment for tobacco cessation - is it worthwhile?]
Journal
Ther Umsch
Author(s)
von Garnier C.
ISSN
0040-5930 (Print)
ISSN-L
0040-5930
Publication state
Published
Issued date
08/2010
Volume
67
Number
8
Pages
431-3
Language
english
Notes
von Garnier, Christophe
ger
Comparative Study
English Abstract
Review
Switzerland
Ther Umsch. 2010 Aug;67(8):431-3. doi: 10.1024/0040-5930/a000076.
Abstract
Though different treatment modalities currently exist for tobacco cessation, many smokers still relapse following an initially successful quitting attempt. We herein provide a selected overview of tobacco relapse prevention strategies evaluated in different trials and in a recent meta-analysis. Most studies were characterised by an inadequate study design and insufficient numbers of participants. Randomised studies, both in selected (hospitalisation, pregnancy, military conscripts) and in unselected smoker groups showed no advantage of psychological interventions, mainly behavioural skills-based approaches. This was independent of whether smokers had been enrolled prior or after quitting tobacco. Pharmacological trials identified no benefit of preventive interventions with nicotine replacement treatments or Bupropion, but one study with prolonged Varenicline treatment significantly reduced the rate of relapse. Currently there is insufficient evidence to recommend systematic preventive relapse treatment for tobacco addiction with psychological or pharmacological interventions. Extended treatment with Varenicline may reduce relapse rates following tobacco cessation. Further meticulously designed and appropriately powered trials will be necessary to clarify the role of alternative psychological and pharmacological strategies for the prevention of relapse after tobacco cessation.
Keywords
Antidepressive Agents/administration & dosage, Behavior Therapy, Benzazepines/administration & dosage, Bupropion/administration & dosage, Humans, Nicotine/administration & dosage, Nicotinic Agonists/administration & dosage, Quinoxalines/administration & dosage, Randomized Controlled Trials as Topic, *Secondary Prevention, Smoking Cessation/*methods, Treatment Outcome, Varenicline
Pubmed
Create date
15/04/2021 9:58
Last modification date
01/05/2021 5:33
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