Post-H1N1 Flu Vaccination Narcolepsy in Switzerland: A Retrospective Survey in the 30 Sleep-Certified Swiss Centers.

Détails

ID Serval
serval:BIB_67D46008CD04
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Post-H1N1 Flu Vaccination Narcolepsy in Switzerland: A Retrospective Survey in the 30 Sleep-Certified Swiss Centers.
Périodique
European Neurology
Auteur(s)
Kallweit U., Mathis J., Jenni O.G., Heinzer R., Haba-Rubio J., Baumann C.R., Cervena K., Bassetti C.L.
ISSN
1421-9913 (Electronic)
ISSN-L
0014-3022
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
75
Numéro
3-4
Pages
105-108
Langue
anglais
Résumé
Narcolepsy-cataplexy is a sleep-wake disorder and suggested to be immune-mediated, involving genetic and environmental factors. The autoimmune process eventually leads to a loss of hypocretin neurons in the lateral hypothalamus. Epidemiological studies in several countries proved an increased incidence of narcolepsy after H1N1 flu vaccination and infection. This survey in 30 sleep centers in Switzerland led to the identification of 9 H1N1-vaccinated children and adults as newly diagnosed narcolepsy. Clinical features included the abrupt and severe onset of sleepiness, cataplexy and sleep fragmentation.
Pubmed
Web of science
Création de la notice
03/06/2016 19:02
Dernière modification de la notice
20/08/2019 15:23
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