Research Progress in Head and Neck Squamous Cell Carcinoma: Best Abstracts of ICHNO 2015.

Détails

ID Serval
serval:BIB_67B8AEDDA73E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Research Progress in Head and Neck Squamous Cell Carcinoma: Best Abstracts of ICHNO 2015.
Périodique
American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting
Auteur(s)
Economopoulou P., Bourhis J., Psyrri A.
ISSN
1548-8756 (Electronic)
ISSN-L
1548-8748
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Pages
e323-e328
Langue
anglais
Résumé
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous group of tumors that develop via one of the two primary carcinogenic pathways: chemical carcinogenesis through exposure to tobacco and alcohol or virally induced tumorigenesis. HPV-negative (HPV-) and HPV-positive (HPV+) HNSCCs represent distinct disease entities, and the latter is associated with a substantially improved outcome. Differences in molecular pathogenesis account for these different outcomes; their staging classification and therapeutic regimens also are currently being re-evaluated, and re-evaluation would be significantly facilitated by robust biomarkers for patient stratification. Through the past years, with the advent of the omics era, a better understanding of the biology of HNSCC has been accompanied by the exploration of a large and rapidly expanding number of targeted agents, which might be incorporated into standard management in the future. In the era of personalized medicine, and with a view to improve the outcomes and quality of life of patients, current research efforts also are focused on the identification of specific biomarkers for treatment selection. Treatment of HNSCC is expected to change in the next decade if molecular biology continues to evolve. Herein, we highlight research progress in HNSCC presented at the fifth International Conference on Innovative Approaches in Head and Neck Oncology (ICHNO).
Mots-clé
Antineoplastic Agents/therapeutic use, Carcinoma, Squamous Cell/pathology, Carcinoma, Squamous Cell/therapy, Early Detection of Cancer, Head and Neck Neoplasms/pathology, Head and Neck Neoplasms/therapy, Humans, Immunotherapy/trends, Meta-Analysis as Topic, Methotrexate/therapeutic use, Molecular Diagnostic Techniques, Molecular Targeted Therapy, Multicenter Studies as Topic, Neoplasm Metastasis, Neoplasm Recurrence, Local, Neoplasm Staging, Oropharyngeal Neoplasms/pathology, Oropharyngeal Neoplasms/therapy, Papillomavirus Vaccines/therapeutic use, Postoperative Care, Precision Medicine/methods, Quinazolines/therapeutic use, Radiotherapy, Adjuvant/methods, Randomized Controlled Trials as Topic, Therapies, Investigational/trends
Pubmed
Création de la notice
20/02/2016 16:02
Dernière modification de la notice
20/08/2019 14:23
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