MRSA screening by the Xpert MRSA PCR assay: pooling samples of the nose, throat, and groin increases the sensitivity of detection without increasing the laboratory costs.
Details
State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_675332C00CE1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
MRSA screening by the Xpert MRSA PCR assay: pooling samples of the nose, throat, and groin increases the sensitivity of detection without increasing the laboratory costs.
Journal
European Journal of Clinical Microbiology and Infectious Diseases
ISSN
1435-4373 (Electronic)
ISSN-L
0934-9723
Publication state
Published
Issued date
2013
Volume
32
Number
4
Pages
565-568
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
The performance of the Xpert MRSA polymerase chain reaction (PCR) assay on pooled nose, groin, and throat swabs (three nylon flocked eSwabs into one tube) was compared to culture by analyzing 5,546 samples. The sensitivity [0.78, 95 % confidence interval (CI) 0.73-0.82] and specificity (0.99, 95 % CI 0.98-0.99) were similar to the results from published studies on separated nose or other specimens. Thus, the performance of the Xpert MRSA assay was not affected by pooling the three specimens into one assay, allowing a higher detection rate without increasing laboratory costs, as compared to nose samples alone.
Pubmed
Web of science
Create date
12/04/2013 18:19
Last modification date
20/08/2019 15:22
Usage data
