Outcomes after surgical treatment for type A acute aortic dissection in octogenarians: a multicenter study.

Details

Serval ID
serval:BIB_67052D5E8A33
Type
Article: article from journal or magazin.
Collection
Publications
Title
Outcomes after surgical treatment for type A acute aortic dissection in octogenarians: a multicenter study.
Journal
The Annals of thoracic surgery
Author(s)
Piccardo A., Regesta T., Zannis K., Gariboldi V., Pansini S., Tapia M., Concistré G., Collart F., Kreitmann P., Kirsch M.E., Martinelli L., Passerone G., Caus T.
ISSN
1552-6259 (Electronic)
ISSN-L
0003-4975
Publication state
Published
Issued date
08/2009
Peer-reviewed
Oui
Volume
88
Number
2
Pages
491-497
Language
english
Notes
Publication types: Journal Article ; Multicenter Study
Publication Status: ppublish
Abstract
Management of octogenarian patients with acute type A acute aortic dissection is controversial. This study analyzed the surgical outcomes to identify patients who should undergo operations.
Beginning January 2000, we established a registry including all octogenarian patients operated on for type A acute aortic dissection. We evaluated 57 consecutive patients enrolled up to December 2006. Their median age was 82 (range, 80 to 89 years). Compassionate indication operations were attempted in 2 moribund patients and in 5 presenting with shock associated with neurologic symptoms or renal failure, or both. Operations followed the standard procedure recommended in younger patients. Follow-up was 100% complete (mean, 3.9 +/- 2 years; range, 5 months to 8 years).
There were 26 (45.6%) in-hospital and 6 late deaths. Multivariate analysis identified compassionate indication (p < or = 0.0001) and total arch replacement (p = 0.0060) as risk factors for in-hospital mortality. Postoperative complications occurred in 36 patients (69.2%) and were associated with a higher mortality (p = 0.0001). Overall survival was 51% at 1 year and 44% at 5 years. Excluding patients with compassionate indication and those who underwent total arch replacement, or both, overall survival was 66% at 1 year and 57% at 5 years.
Surgical treatment for type A acute aortic dissection in octogenarians shows satisfactory midterm results among survivors. However, the high mortality rate imposes a requirement for better perioperative management. Compassionate cases should be managed medically. A less aggressive approach should improve outcomes of surgical treatment.
Keywords
Aged, 80 and over, Aneurysm, Dissecting/mortality, Aneurysm, Dissecting/surgery, Aortic Aneurysm/mortality, Aortic Aneurysm/surgery, Female, Heart Failure/mortality, Hospital Mortality, Humans, Length of Stay, Male, Multivariate Analysis, Postoperative Complications/epidemiology, Prognosis, Registries, Risk Factors, Treatment Outcome
Pubmed
Web of science
Create date
29/03/2019 8:09
Last modification date
20/08/2019 15:22
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