Management of pediatric keratoconus - evolving role of corneal collagen cross-linking: an update.

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Version: Final published version
License: CC BY-NC-SA 4.0
Serval ID
serval:BIB_66A14BBA1CB2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Management of pediatric keratoconus - evolving role of corneal collagen cross-linking: an update.
Journal
Indian journal of ophthalmology
Author(s)
Kankariya V.P., Kymionis G.D., Diakonis V.F., Yoo S.H.
ISSN
1998-3689 (Electronic)
ISSN-L
0301-4738
Publication state
Published
Issued date
08/2013
Peer-reviewed
Oui
Volume
61
Number
8
Pages
435-440
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Pediatric keratoconus demonstrates several distinctive management issues in comparison with adult keratoconus with respect to under-diagnosis, poor compliance and modifications in treatment patterns. The major concerns comprise of the accelerated progression of the disease in the pediatric age group and management of co-morbidities such as vernal keratoconjuntivitis. Visual impairment in pediatric patients may affect social and educational development and overall negatively impact their quality of life. The treatment algorithm between adults and pediatric keratoconus has been similar; comprising mainly of visual rehabilitation with spectacles, contacts lenses (soft or rigid) and keratoplasty (lamellar or penetrating) depending on the stage of the disease. There is a paradigm shift in the management of keratoconus, a new treatment modality, corneal collagen crosslinking (CXL), has been utilized in adult keratoconic patients halting the progression of the disease. CXL has been utilized for over a 10 year period and based on the evidence of efficacy and safety in the adult population; this treatment has been recently utilized in management of pediatric keratoconus. This article will present an update about current management of pediatric keratoconus with special focus on CXL in this age group.
Keywords
Adolescent, Child, Collagen/metabolism, Corneal Stroma/metabolism, Cross-Linking Reagents/therapeutic use, Disease Progression, Humans, Keratoconus/diagnosis, Keratoconus/drug therapy, Keratoconus/metabolism, Photochemotherapy/methods, Photosensitizing Agents/therapeutic use, Riboflavin/therapeutic use, Ultraviolet Rays, Vision Disorders/rehabilitation
Pubmed
Web of science
Open Access
Yes
Create date
01/10/2019 13:57
Last modification date
12/01/2022 8:10
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