Exploring protective and risk factors in the home environment in high-risk families - results from the Danish High Risk and Resilience Study-VIA 7.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_6480F0A63570
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Exploring protective and risk factors in the home environment in high-risk families - results from the Danish High Risk and Resilience Study-VIA 7.
Journal
BMC psychiatry
Author(s)
Thorup AAE, Gantriis D.L., Greve A.N., Henriksen M.T., Zahle K.K., Stadsgaard H., Ellersgaard D., Burton B.K., Christiani C.J., Spang K., Hemager N., Jepsen JRM, Plessen K.J., Nordentoft M., Mors O., Bliksted V.
ISSN
1471-244X (Electronic)
ISSN-L
1471-244X
Publication state
Published
Issued date
09/02/2022
Peer-reviewed
Oui
Volume
22
Number
1
Pages
100
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder.
From a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment.
When analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately.
Knowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.
Keywords
Bipolar Disorder/diagnosis, Bipolar Disorder/genetics, Child, Child, Preschool, Denmark, Female, Genetic Predisposition to Disease, Home Environment, Humans, Risk Factors, Bipolar disorder, Familial high-risk, Home environment, Risk factors, Schizophrenia
Pubmed
Web of science
Open Access
Yes
Create date
20/02/2022 11:23
Last modification date
23/01/2024 7:26
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