Article: article from journal or magazin.
Younger age as a bad prognostic factor in patients with carcinoma of the cervix.
European journal of obstetrics, gynecology, and reproductive biology
Publication types: Journal Article - Publication Status: ppublish
OBJECTIVE: To verify the influence of age on the prognosis of cervix carcinoma. STUDY DESIGN: Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: < or = 45, 46-60, 61-69 and >70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis. RESULTS: The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages. CONCLUSION: Age under 45 years is a bad prognostic factor in carcinoma of the cervix.
Adult, Age Factors, Aged, Carcinoma, Combined Modality Therapy, Female, Humans, Middle Aged, Neoplasm Staging, Prognosis, Survival Rate, Uterine Cervical Neoplasms
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