Significance of circulating antibodies directed against the Kveim suspension demonstrated in patients with sarcoidosis

Details

Serval ID
serval:BIB_6366AA73EF63
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Significance of circulating antibodies directed against the Kveim suspension demonstrated in patients with sarcoidosis
Journal
Journal of Clinical and Laboratory Immunology
Author(s)
Favez  G., Leuenberger  P.
ISSN
0141-2760 (Print)
Publication state
Published
Issued date
11/1982
Volume
9
Number
2
Pages
87-91
Notes
Journal Article --- Old month value: Nov
Abstract
A hemagglutination test using coated sheep erythrocytes was devised for quantifying circulating antibodies directed against an extract of sarcoid spleen (K veim suspension). Out of 361 patients with respiratory sarcoidosis, the titres for 336 were less than 1:1,280. In 335 patients with various disorders the titres were less than 1:1,280 in 29. In 151 healthy controls the titres were never found to be less than 1:160. The circulating antibodies seemed to react specifically with antigenic determinant(s) contained in the K veim suspension and belonged primarily to the IgM class.
Keywords
Antibodies, Anti-Idiotypic/analysis Autoantibodies/analysis Humans Immunoglobulin M/immunology Sarcoidosis/diagnosis/*immunology Spleen/*immunology
Pubmed
Web of science
Create date
25/01/2008 9:49
Last modification date
20/08/2019 14:20
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