Lower limb lymphedema and neurological complications after lymphadenectomy for gynecological cancer.

Détails

ID Serval
serval:BIB_63048B349D18
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Lower limb lymphedema and neurological complications after lymphadenectomy for gynecological cancer.
Périodique
International journal of gynecological cancer
Auteur(s)
Biglia N., Librino A., Ottino M.C., Panuccio E., Daniele A., Achtari C.
ISSN
1525-1438 (Electronic)
ISSN-L
1048-891X
Statut éditorial
Publié
Date de publication
03/2015
Peer-reviewed
Oui
Volume
25
Numéro
3
Pages
521-525
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Lymphadenectomy is a frequent procedure for surgical staging of gynecological malignancies. Nevertheless, minor complications, such as lower limb lymphedema (LLL) and neurological complications (NCs), after pelvic and aorto-caval lymphadenectomy still remain underinvestigated. The present study considers short-term and long-term incidence and risk factors for LLL and NC in patients with gynecological cancer who underwent lymphadenectomy.
In 2 different institutions, University of Turin and University of Lausanne, a total of 152 patients who received lymphadenectomy for endometrial, cervical, or ovarian cancer were retrospectively identified. During the follow-up, data about LLL and NC were collected by means of a questionnaire. Short-term and long-term incidence of LLL and NC was evaluated, and risk factors, such as age, body mass index, type of cancer, surgical approach, number and extension of the removed lymph nodes, presence of lymph node metastasis, and adjuvant treatments, were analyzed.
Short-term incidence of LLL and NC after lymphadenectomy was high (36%) and predictive of long-term persistence. Between the analyzed risk factors, number of removed lymph nodes and adjuvant radiotherapy were significantly associated with an increased incidence of minor complications (P < 0.05).
Lower limb lymphedema and NC are more frequent than expected. They are related to the radicality of lymphadenectomy and adjuvant radiotherapy. They affect the quality of life of the patients treated for gynecological cancer and their perceptions of healing. Minor complications are commonly persistent and need a prompt diagnosis and a specialized management to improve their prognosis.

Mots-clé
Adult, Aged, Aged, 80 and over, Female, Genital Neoplasms, Female/therapy, Humans, Incidence, Lower Extremity, Lumbosacral Plexus/injuries, Lymph Node Excision/adverse effects, Lymphedema/epidemiology, Lymphedema/etiology, Middle Aged, Peripheral Nerve Injuries/complications, Peripheral Nervous System Diseases/epidemiology, Peripheral Nervous System Diseases/etiology, Radiotherapy, Adjuvant/adverse effects, Risk Factors, Time Factors
Pubmed
Web of science
Création de la notice
02/04/2015 19:30
Dernière modification de la notice
20/08/2019 14:19
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