Duplication and concerted evolution in a master sex determiner under balancing selection.

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Etat: Public
Version: de l'auteur
Licence: Non spécifiée
ID Serval
serval:BIB_61EF8E83CFA6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Duplication and concerted evolution in a master sex determiner under balancing selection.
Périodique
Proceedings of the Royal Society of London B Biological Sciences
Auteur(s)
Privman E., Wurm Y., Keller L.
ISSN
1471-2954 (Electronic)
ISSN-L
0962-8452
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
280
Numéro
1758
Pages
20122968
Langue
anglais
Résumé
The transformer (tra) gene is a key regulator in the signalling hierarchy controlling all aspects of somatic sexual differentiation in Drosophila and other insects. Here, we show that six of the seven sequenced ants have two copies of tra. Surprisingly, the two paralogues are always more similar within species than among species. Comparative sequence analyses indicate that this pattern is owing to the ongoing concerted evolution after an ancestral duplication rather than independent duplications in each of the six species. In particular, there was strong support for inter-locus recombination between the paralogues of the ant Atta cephalotes. In the five species where the location of paralogues is known, they are adjacent to each other in four cases and separated by only few genes in the fifth case. Because there have been extensive genomic rearrangements in these lineages, this suggests selection acting to conserve their synteny. In three species, we also find a signature of positive selection in one of the paralogues. In three bee species where information is available, the tra gene is also duplicated, the copies are adjacent and in at least one species there was recombination between paralogues. These results suggest that concerted evolution plays an adaptive role in the evolution of this gene family.
Mots-clé
sex determination, transformer, gene duplication, concerted evolution, Hymenoptera
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/03/2013 18:23
Dernière modification de la notice
23/08/2019 6:08
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