Study of common database feeding with results coming from different analytical methods in the framework of illicit drugs chemical profiling

Details

Serval ID
serval:BIB_618AF1B875B0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Study of common database feeding with results coming from different analytical methods in the framework of illicit drugs chemical profiling
Journal
Forensic Science International
Author(s)
Broséus J., Debrus B., Delémont O., Rudaz S., Esseiva P.
ISSN
1872-6283
ISSN-L
0379-0738
Publication state
Published
Issued date
07/2013
Peer-reviewed
Oui
Volume
230
Number
1-3
Pages
16-28
Language
english
Abstract
Analytical results harmonisation is investigated in this study to provide an alternative to the restrictive approach of analytical methods harmonisation which is recommended nowadays for making possible the exchange of information and then for supporting the fight against illicit drugs trafficking.
Indeed, the main goal of this study is to demonstrate that a common database can be fed by a range of different analytical methods, whatever the differences in levels of analytical parameters between these latter ones. For this purpose, a methodology making possible the estimation and even the optimisation of results similarity coming from different analytical methods was then developed.
In particular, the possibility to introduce chemical profiles obtained with Fast GC-FID in a GC-MS database is studied in this paper. By the use of the methodology, the similarity of results coming from different analytical methods can be objectively assessed and the utility in practice of database sharing by these methods can be evaluated, depending on profiling purposes (evidential vs. operational perspective tool).
This methodology can be regarded as a relevant approach for database feeding by different analytical methods and puts in doubt the necessity to analyse all illicit drugs seizures in one single laboratory or to implement analytical methods harmonisation in each participating laboratory.
Keywords
Analytical results harmonisation, Analytical methods harmonisation, GC-MS, Fast GC-FID, Chemical profiles similarity, Mathematical adjustment
Create date
01/07/2013 9:00
Last modification date
20/08/2019 14:18
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