Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia.

Détails

ID Serval
serval:BIB_6157DFA6A6AE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia.
Périodique
Vaccine
Auteur(s)
Ventura R., Brunner L., Heriyanto B., de Boer O., O'Hara M., Huynh C., Suhardono M., Collin N.
ISSN
1873-2518 (Electronic)
ISSN-L
0264-410X
Statut éditorial
Publié
Date de publication
2013
Volume
31
Numéro
12
Pages
1641-1645
Langue
anglais
Résumé
With the current enzootic circulation of highly pathogenic avian influenza viruses, the ability to increase global pandemic influenza vaccine production capacity is of paramount importance. This has been highlighted by, and is one of the main pillars of, the WHO Global Action Plan for Influenza Vaccines (GAP). Such capacity expansion is especially relevant in developing countries. The Vaccine Formulation Laboratory at University of Lausanne is engaged in the technology transfer of an antigen-sparing oil-in-water adjuvant in order to empower developing countries vaccine manufacturers to increase pandemic influenza vaccine capacity. In a one-year project funded by United States Department of Health and Human Services, the Vaccine Formulation Laboratory transferred the process know-how and associated equipment for the pilot-scale manufacturing of an oil-in-water adjuvant to Bio Farma, Indonesia's state-owned vaccine manufacturer, for subsequent formulation with H5N1 pandemic influenza vaccines. This paper describes the experience acquired and lessons learnt from this technology transfer project.
Mots-clé
Technology transfer, Oil-in-water adjuvant, Pandemic influenza vaccine, Vaccine formulation
Pubmed
Web of science
Création de la notice
22/01/2013 9:45
Dernière modification de la notice
20/08/2019 15:18
Données d'usage