Associations between lung function and estimated average exposure to NO2 in eight areas of Switzerland. The SAPALDIA Team. Swiss Study of Air Pollution and Lung Diseases in Adults

Details

Serval ID
serval:BIB_6133243FAE4F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Associations between lung function and estimated average exposure to NO2 in eight areas of Switzerland. The SAPALDIA Team. Swiss Study of Air Pollution and Lung Diseases in Adults
Journal
Epidemiology
Author(s)
Schindler  C., Ackermann-Liebrich  U., Leuenberger  P., Monn  C., Rapp  R., Bolognini  G., Bongard  J. P., Brandli  O., Domenighetti  G., Karrer  W., Keller  R., Medici  T. G., Perruchoud  A. P., Schoni  M. H., Tschopp  J. M., Villiger  B., Zellweger  J. P.
ISSN
1044-3983 (Print)
Publication state
Published
Issued date
07/1998
Volume
9
Number
4
Pages
405-11
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jul
Abstract
In this paper, we present results from the SAPALDIA study (Swiss Study on Air Pollution and Lung Diseases in Adults) regarding associations between lung function [forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1)], as assessed during the cross-sectional study in 1991, and average levels of NO2 exposure within the eight study communities. We distinguished average home outdoor exposure and average personal exposure to NO2 and obtained exposure estimates by computing regional averages of passive sampler measurements performed by a random subsample of SAPALDIA participants in 1993. Previous analyses had revealed associations between average lung function and average air pollution levels between communities. The present results show that such associations may also be seen within communities: a 10-micrograms per m3 increase in average home outdoor and personal exposure to NO2 between zones of residence of the same community was associated with a change in average FVC by -0.59% [95% confidence limits (CL) = 0.01, -1.19] and -0.74% (95% CL = -0.07, -1.41), respectively. These values, however, are smaller than the ones found for the corresponding associations between study communities: -1.67% (95% CL = -1.01, -2.33) and -2.93% (95% CL = -2.11, -3.75), respectively. The different magnitudes of these two types of associations might be explained by differences in spatial variation between various components of air pollution.
Keywords
Adult Air Pollutants/*adverse effects/analysis Air Pollution/*adverse effects/analysis/statistics & numerical data Cohort Studies Confidence Intervals Cross-Sectional Studies Environmental Exposure/*adverse effects/analysis/statistics & numerical data Environmental Monitoring/methods/statistics & numerical data Female Forced Expiratory Volume/drug effects Humans Male Middle Aged Nitrogen Dioxide/*adverse effects/analysis Regression Analysis Respiratory Mechanics/*drug effects Switzerland Vital Capacity/drug effects
Pubmed
Web of science
Create date
25/01/2008 9:50
Last modification date
20/08/2019 14:18
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