An ontology to clarify homology-related concepts.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_611EAEEC4DD5
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
An ontology to clarify homology-related concepts.
Périodique
Trends in Genetics
Auteur(s)
Roux J., Robinson-Rechavi M.
ISSN
0168-9525 (Print)
ISSN-L
0168-9525
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
26
Numéro
3
Pages
99-102
Langue
anglais
Résumé
Although homology is a fundamental concept in biology and is one of the shared channels of communication universal to all biology, it is difficult to find a consensus definition. Indeed, the interpretations of homology have changed as biology has progressed. New terms, such as paramorphism, have been introduced into the literature with mixed success. In addition, different research fields operate with different definitions of homology, for example the mechanistic usage of evo-devo is not strictly historical and would not be acceptable in cladistics. This makes a global understanding of homology complex, whereas the integration of evolutionary concepts into bioinformatics and genomics is increasingly important. We propose an ontology organizing homology and related concepts and hope this solution will also facilitate the integration and sharing of knowledge among the community.
Mots-clé
Animals, Biological Evolution, Computational Biology, Humans, Models, Genetic
Pubmed
Web of science
Open Access
Oui
Création de la notice
04/01/2010 10:34
Dernière modification de la notice
20/08/2019 14:18
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