Evolutionary and biomedical consequences of internal melanins.

Détails

Ressource 1Demande d'une copie Sous embargo indéterminé.
Etat: Public
Version: Final published version
ID Serval
serval:BIB_5FE774D78F6D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Evolutionary and biomedical consequences of internal melanins.
Périodique
Pigment Cell and Melanoma Research
Auteur(s)
Dubey S., Roulin A.
ISSN
1755-148X (Electronic)
ISSN-L
1755-1471
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
27
Numéro
3
Pages
327-338
Langue
anglais
Résumé
The adaptive function of melanin located in the integument is well known. Although pigments are also deposited in various internal organs, their function is unclear. A review of the literature revealed that 'internal melanin' protects against parasites, pollutants, low temperature, oxidative stress, hypoxemia and UV light, and is involved in the development and function of organs. Importantly, several studies have shown that the amount of melanin deposited on the external body surface is correlated with the amount located inside the body. This finding raises the possibility that internal melanin plays more important physiological roles in dark than light-colored individuals. Internal melanin and coloration may therefore not evolve independently. This further emphasizes the major role played by indirect selection in evolutionary processes.
Mots-clé
melanin, neuromelanin, melanocyte, coloration, oxidative stress, pollutant, parasite
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/02/2014 16:31
Dernière modification de la notice
20/08/2019 14:17
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