Radial Ultrasound-Assisted Transbronchial Biopsy: A New Diagnostic Approach for Non-Resolving Pulmonary Infiltrates in Neutropenic Hemato-Oncological Patients.

Détails

ID Serval
serval:BIB_5FC2874DDD0E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Radial Ultrasound-Assisted Transbronchial Biopsy: A New Diagnostic Approach for Non-Resolving Pulmonary Infiltrates in Neutropenic Hemato-Oncological Patients.
Périodique
Lung
Auteur(s)
Bernasconi M., Casutt A., Koutsokera A., Letovanec I., Tissot F., Nicod L.P., Lovis A.
ISSN
1432-1750 (Electronic)
ISSN-L
0341-2040
Statut éditorial
Publié
Date de publication
12/2016
Peer-reviewed
Oui
Volume
194
Numéro
6
Pages
917-921
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The role of radial-endobronchial ultrasound (R-EBUS) assisted transbronchial biopsy (TBB) for the diagnosis of peripheral pulmonary lesions is well established. However, no study has addressed its safety and value in hemato-oncological patients presenting with non-resolving infiltrates during persistent febrile neutropenia. To assess safety and feasibility of R-EBUS assisted TBB in severe thrombocytopenic and neutropenic patients. Over a period of 18 months, eight patients were assessed with R-EBUS assisted TBB after adequate platelet transfusion. This technique allowed precise localisation and sampling of the pulmonary lesions in seven of eight patients. In the seven patients, R-EBUS assisted TBB enabled treatment optimization. Invasive fungal infection was diagnosed in four patients, idiopathic acute fibrinous and organising pneumonia in three patients, and a granulomatous inflammation of undetermined origin in one patient. Importantly, no complications, such as bleeding, were observed. R-EBUS assisted TBB is a promising and safe procedure for the evaluation of nonresolving pulmonary infiltrates in febrile neutropenic hemato-oncological patients.
Mots-clé
Adult, Aged, Antineoplastic Agents/adverse effects, Endosonography/adverse effects, Endosonography/methods, Feasibility Studies, Granuloma, Respiratory Tract/diagnosis, Hematologic Neoplasms/complications, Hematologic Neoplasms/drug therapy, Humans, Idiopathic Pulmonary Fibrosis/diagnosis, Idiopathic Pulmonary Fibrosis/etiology, Image-Guided Biopsy/adverse effects, Invasive Fungal Infections/diagnosis, Invasive Fungal Infections/microbiology, Middle Aged, Neutropenia/chemically induced, Neutropenia/complications, Pneumonia/diagnosis, Pneumonia/etiology, Acute fibrinous and organising pneumonia, Non-resolving pulmonary infiltrates, Radial-endobronchial ultrasound, persistent febrile neutropenia
Pubmed
Web of science
Création de la notice
19/10/2016 8:13
Dernière modification de la notice
20/08/2019 15:17
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