KnotProt: a database of proteins with knots and slipknots.

Détails

Ressource 1Télécharger: 25361973_BIB_5E3AE35DDBFA.pdf (1854.92 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_5E3AE35DDBFA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
KnotProt: a database of proteins with knots and slipknots.
Périodique
Nucleic Acids Research
Auteur(s)
Jamroz M., Niemyska W., Rawdon E.J., Stasiak A., Millett K.C., Sulkowski P., Sulkowska J.I.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Statut éditorial
Publié
Date de publication
2015
Volume
43
Numéro
Database issue
Pages
D306-D314
Langue
anglais
Résumé
The protein topology database KnotProt, http://knotprot.cent.uw.edu.pl/, collects information about protein structures with open polypeptide chains forming knots or slipknots. The knotting complexity of the cataloged proteins is presented in the form of a matrix diagram that shows users the knot type of the entire polypeptide chain and of each of its subchains. The pattern visible in the matrix gives the knotting fingerprint of a given protein and permits users to determine, for example, the minimal length of the knotted regions (knot's core size) or the depth of a knot, i.e. how many amino acids can be removed from either end of the cataloged protein structure before converting it from a knot to a different type of knot. In addition, the database presents extensive information about the biological functions, families and fold types of proteins with non-trivial knotting. As an additional feature, the KnotProt database enables users to submit protein or polymer chains and generate their knotting fingerprints.
Mots-clé
Databases, Protein, Peptides/chemistry, Protein Conformation
Pubmed
Web of science
Open Access
Oui
Création de la notice
14/04/2015 8:54
Dernière modification de la notice
20/08/2019 14:16
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