Simultaneous assessment of vascular distensibility and vessel wall area at coronary, carotid, and aortic level in diabetic patients using CMR: detection of vascular remodeling.
Details
Serval ID
serval:BIB_5DF1A691EA5C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Simultaneous assessment of vascular distensibility and vessel wall area at coronary, carotid, and aortic level in diabetic patients using CMR: detection of vascular remodeling.
Journal
American journal of cardiovascular disease
ISSN
2160-200X (Print)
ISSN-L
2160-200X
Publication state
Published
Issued date
04/2023
Peer-reviewed
Oui
Volume
13
Number
2
Pages
73-86
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
No data is available about the significance of cardiovascular magnetic resonance (CMR) derived vascular distensibility (VD) and vessel wall ratio (VWR) for risk stratification in patients with type 2 diabetes mellitus (T2DM). Therefore, this study aimed to investigate the effects of T2DM on VD and VWR using CMR in both central and peripheral territories.
Thirty-one T2DM-patients and nine controls underwent CMR. Angulation of the aorta, the common carotid, and the coronary arteries was performed to obtain cross-sectional vessel areas.
In T2DM the Carotid-VWR and the Aortic-VWR correlated significantly. Mean values of Carotid-VWR and Aortic-VWR were significantly higher in T2DM than in controls. Coronary-VD was significantly lower in T2DM than in controls. No significant difference in Carotid-VD or Aortic-VD in T2DM vs. controls, respectively, could be observed. In a subgroup of thirteen T2DM patients with coronary artery disease (CAD), Coronary-VD was significantly lower and Aortic-VWR was significantly higher compared to T2DM patients without CAD.
CMR allows a simultaneous evaluation of the structure and function of three important vascular territories to detect vascular remodeling in T2DM.
Thirty-one T2DM-patients and nine controls underwent CMR. Angulation of the aorta, the common carotid, and the coronary arteries was performed to obtain cross-sectional vessel areas.
In T2DM the Carotid-VWR and the Aortic-VWR correlated significantly. Mean values of Carotid-VWR and Aortic-VWR were significantly higher in T2DM than in controls. Coronary-VD was significantly lower in T2DM than in controls. No significant difference in Carotid-VD or Aortic-VD in T2DM vs. controls, respectively, could be observed. In a subgroup of thirteen T2DM patients with coronary artery disease (CAD), Coronary-VD was significantly lower and Aortic-VWR was significantly higher compared to T2DM patients without CAD.
CMR allows a simultaneous evaluation of the structure and function of three important vascular territories to detect vascular remodeling in T2DM.
Keywords
CMR, Coronary artery disease, aorta distensibility, cardiac MRI, caritid, cross-sectional studies, diabetes mellitus, magnetic resonance imaging, type 2, vascular remodeling
Pubmed
Web of science
Create date
30/05/2023 10:22
Last modification date
21/10/2023 6:09
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