Successful Pre-Rewarming Resuscitation after Cardiac Arrest in Severe Hypothermia: A Retrospective Cohort Study from the International Hypothermia Registry.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_5B103DD0845E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Successful Pre-Rewarming Resuscitation after Cardiac Arrest in Severe Hypothermia: A Retrospective Cohort Study from the International Hypothermia Registry.
Journal
International journal of environmental research and public health
Author(s)
Cools E., Meyer M., Courvoisier D., Walpoth B.
ISSN
1660-4601 (Electronic)
ISSN-L
1660-4601
Publication state
Published
Issued date
29/03/2022
Peer-reviewed
Oui
Volume
19
Number
7
Pages
4059
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
The aim of our study is to investigate successful pre-rewarming resuscitation after hypothermic cardiac arrest (HCA). The hypothermic heart may be insensitive to defibrillation when core temperature is below 30 °C and after successful defibrillation, sinus rhythm often returns into ventricular fibrillation. Recurrent defibrillation attempts may induce myocardial injury. Discrepancy exists concerning pre-rewarming defibrillation between the guidelines of the European Resuscitation Council and American Heart Association. The International Hypothermia Registry (IHR) gathers hypothermia cases. The primary outcome was survival. Secondary outcomes were the characteristics of defibrillation, the effect of Adrenaline administration under 30 °C, and the duration of CPR. Of the 239 patients, eighty-eight were in cardiac arrest at arrival of the rescue team. Successful pre-rewarming resuscitation was obtained in 14 patients. The outcome showed: seven deaths, one vegetative state, two patients with reversible damage, and four patients with full recovery. A total of five patients had a shockable rhythm, and defibrillation was successful in four patients. The response rate to Adrenaline was reported as normal in six patients. There were no statistically significant differences in the presence of a shockable rhythm, the success of defibrillation, and the effect on Adrenaline administration between the survivors and non-survivors. Successful resuscitation in severe hypothermia is possible before active rewarming and arrival in the hospital, thus improving the chance of survival.
Keywords
Cardiopulmonary Resuscitation, Epinephrine/therapeutic use, Heart Arrest/therapy, Humans, Hypothermia/therapy, Registries, Retrospective Studies, Rewarming, accidental hypothermia, mountain medicine, resuscitation, rewarming
Pubmed
Web of science
Open Access
Yes
Create date
19/04/2022 14:27
Last modification date
23/01/2024 8:26
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