Idiopathic Intracranial Hypertension-A Comparison of Clinical Characteristics Between 4 Medical Centers in Different Geographic Regions of the World.

Détails

ID Serval
serval:BIB_5B077281859E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Idiopathic Intracranial Hypertension-A Comparison of Clinical Characteristics Between 4 Medical Centers in Different Geographic Regions of the World.
Périodique
Journal of neuro-ophthalmology
Auteur(s)
Rosenblatt A., Klein A., Roemer S., Borruat F.X., Meira D., Silva M., Gökçay F., Çelebisoy N., Kesler A.
ISSN
1536-5166 (Electronic)
ISSN-L
1070-8022
Statut éditorial
Publié
Date de publication
09/2016
Peer-reviewed
Oui
Volume
36
Numéro
3
Pages
280-284
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Idiopathic intracranial hypertension (IIH) is a well-characterized syndrome, most commonly affecting obese women of childbearing age. Differences in its prevalence have been reported in various populations. The aim of this article was to determine whether differences in clinical presentation and management exist for patients with IIH between different regions the world.
Retrospective database analysis of adult patients with IIH from 4 different neuro-ophthalmology clinics. The data collected included gender, age of onset, body mass index (BMI), lumbar puncture opening pressure, initial visual acuity (VA), initial visual field (VF) mean deviation (MD), pharmacological or surgical treatment, length of follow-up, final VA, and final VF MD.
The study population consisted of 244 patients, with significant regional variations of female to male ratio. Overall, there was no significant difference regarding the age of diagnosis or the BMI. Acetazolamide was the first line of treatment in all groups but there was a difference between countries regarding second-line treatment, including the use of surgical interventions. Mean initial VA differed between groups but the final change in VA was the same among all the study groups.
There are differences in IIH presentation, treatment, and response to therapy among different countries. International prospective studies involving multiple centers are needed to determine the potential influence of environmental and genetic factors on the development of IIH and to improve the management of this potentially blinding disorder.

Pubmed
Création de la notice
14/06/2016 17:10
Dernière modification de la notice
20/08/2019 14:14
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