Bgee: integrating and comparing heterogeneous transcriptome data among species

Détails

Ressource 1Télécharger: BIB_5A6F9D63F92D.P001.pdf (157.18 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_5A6F9D63F92D
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Collection
Publications
Titre
Bgee: integrating and comparing heterogeneous transcriptome data among species
Titre de la conférence
Data Integration in Life Sciences
Auteur(s)
Bastian F., Parmentier G., Roux J., Moretti S., Laudet V., Robinson-Rechavi M.
Editeur
Springer
Adresse
Berlin
ISBN
0302-9743
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Editeur scientifique
Istrail S., Pevzner P., Waterman M.
Volume
5109
Série
Lecture Notes in Computer Science
Pages
124-131
Langue
anglais
Notes
5th International Workshop, DILS 2008, Evry, France, June 25-27, 2008. Proceedings
Résumé
Gene expression patterns are a key feature in understanding gene function, notably in development. Comparing gene expression patterns between animals is a major step in the study of gene function as well as of animal evolution. It also provides a link between genes and phenotypes. Thus we have developed Bgee, a database designed to compare expression patterns between animals, by implementing ontologies describing anatomies and developmental stages of species, and then designing homology relationships between anatomies and comparison criteria between developmental stages. To define homology relationships between anatomical features we have developed the software Homolonto, which uses a modified ontology alignment approach to propose homology relationships between ontologies. Bgee then uses these aligned ontologies, onto which heterogeneous expression data types are mapped. These already include microarrays and ESTs.
Mots-clé
gene expression pattern, homology, ontology, data integration
Open Access
Oui
Création de la notice
21/04/2008 14:21
Dernière modification de la notice
08/05/2019 19:02
Données d'usage