Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.

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Ressource 1Télécharger: BIB_5A02614F7662.P001.pdf (1415.44 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_5A02614F7662
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.
Périodique
Genome Biology
Auteur(s)
Santuari L., Pradervand S., Amiguet-Vercher A.M., Thomas J., Dorcey E., Harshman K., Xenarios I., Juenger T.E., Hardtke C.S.
ISSN
1465-6914[electronic], 1465-6906[linking]
Statut éditorial
Publié
Date de publication
2010
Volume
11
Numéro
1
Pages
R4
Langue
anglais
Résumé
ABSTRACT: Identification of small polymorphisms from next generation sequencing short read data is relatively easy, but detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization signal reliably flags deletions. Interestingly, individual deletions were frequently observed in two or more of the accessions examined, suggesting that variation in gene content partly reflects a common history of deletion events.
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/03/2010 15:27
Dernière modification de la notice
20/08/2019 14:13
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