Homoeologs: What Are They and How Do We Infer Them?

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State: Public
Version: Final published version
Serval ID
serval:BIB_59A0CA77B84B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Homoeologs: What Are They and How Do We Infer Them?
Journal
Trends in Plant Science
Author(s)
Glover N.M., Redestig H., Dessimoz C.
ISSN
1878-4372 (Electronic)
ISSN-L
1360-1385
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
21
Number
7
Pages
609-621
Language
english
Abstract
The evolutionary history of nearly all flowering plants includes a polyploidization event. Homologous genes resulting from allopolyploidy are commonly referred to as 'homoeologs', although this term has not always been used precisely or consistently in the literature. With several allopolyploid genome sequencing projects under way, there is a pressing need for computational methods for homoeology inference. Here we review the definition of homoeology in historical and modern contexts and propose a precise and testable definition highlighting the connection between homoeologs and orthologs. In the second part, we survey experimental and computational methods of homoeolog inference, considering the strengths and limitations of each approach. Establishing a precise and evolutionarily meaningful definition of homoeology is essential for understanding the evolutionary consequences of polyploidization.
Pubmed
Web of science
Open Access
Yes
Create date
09/04/2016 15:10
Last modification date
20/08/2019 14:13
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