Qu'avons-nous appris des inhibiteurs du système rénine-angiotensine [What have we learned about inhibitors of the renin-angiotensin system?]

Details

Serval ID
serval:BIB_590FE94A880F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Qu'avons-nous appris des inhibiteurs du système rénine-angiotensine [What have we learned about inhibitors of the renin-angiotensin system?]
Journal
Annales d'Endocrinologie
Author(s)
Waeber B., Nussberger J., Brunner H.R.
ISSN
0003-4266
Publication state
Published
Issued date
1986
Peer-reviewed
Oui
Volume
47
Number
3
Pages
167-177
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Abstract
With orally active angiotensin converting inhibitors it is now possible to block the renin-angiotensin system chronically. These agents given alone normalize blood pressure of many hypertensive patients. In the remaining, an additional salt subtraction, induced for example by diuretics, is necessary to further reduce blood pressure. In patients with congestive heart failure, angiotensin converting enzyme inhibitors increase cardiac output and exercise capacity, both acutely and chronically. Adverse reactions resulting from blockade of the renin-angiotensin system can be predicted to a large extent and therefore are most often easily avoided. Angiotensin converting enzyme inhibitors like captopril and enalapril, because of their efficacy and good acceptability are likely to become important drugs for the treatment of hypertension and congestive heart failure.
Keywords
Angiotensin-Converting Enzyme Inhibitors, Blood Pressure/drug effects, Cardiovascular Diseases/drug therapy, Heart Failure/drug therapy, Heart Failure/physiopathology, Hemodynamics/drug effects, Humans, Hypertension/drug therapy, Hypertension/physiopathology, Renin-Angiotensin System/drug effects
Pubmed
Web of science
Create date
05/03/2008 16:39
Last modification date
20/08/2019 14:12
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