Article: article d'un périodique ou d'un magazine.
Traitement du cancer larynge: cordectomie ou crico-hyoidoepiglottopexie versus radiotherapie. [Treatment of laryngeal cancer: cordectomy or crico-hyoido-epiglottopexy versus radiotherapy]
Schweizerische Medizinische Wochenschrift. Supplementum
Date de publication
Comparative Study English Abstract Journal Article
INTRODUCTION: Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments. METHODS: Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups. RESULTS: Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery). CONCLUSION: The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.
Carcinoma, Squamous Cell/pathology/radiotherapy/*surgery Cricoid Cartilage/pathology/radiation effects/surgery Epiglottis/pathology/radiation effects/surgery Follow-Up Studies Humans Hyoid Bone/pathology/radiation effects/surgery Laryngeal Neoplasms/pathology/radiotherapy/*surgery Laryngectomy/*methods *Laryngoscopy Neoplasm Staging Retrospective Studies Treatment Outcome
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