Altered structural connectivity in patients with medial temporal lobe epilepsy: A Diffusion Spectrum Imaging and Graph Analysis study
Details
Serval ID
serval:BIB_5756A2F13C00
Type
Inproceedings: an article in a conference proceedings.
Collection
Publications
Institution
Title
Altered structural connectivity in patients with medial temporal lobe epilepsy: A Diffusion Spectrum Imaging and Graph Analysis study
Title of the conference
ISMRM 2012, 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine, SMRT 21st Annual Meeting of the Section for Magnetic Resonance Technologists conference
Address
Melbourne, Australia, May 5-11, 2012
ISBN
1557-3672
Publication state
Published
Issued date
2012
Volume
20
Series
Proceedings of the International Society for Magnetic Resonance in Medicine
Pages
?
Language
english
Abstract
In this study we investigated the effect of medial
temporal lobe epilepsy (MTLE) on the global
characteristics of brain connectivity estimated by
topological measures. We used DSI (Diffusion Spectrum
Imaging) to construct a connectivity matrix where the
nodes represents the anatomical ROIs and the edges are
the connections between any pair of ROIs weighted by the
mean GFA/FA values. A significant difference was found
between the patient group vs control group in
characteristic path length, clustering coefficient and
small-worldness. This suggests that the MTLE network is
less efficient compared to the network of the control
group.
temporal lobe epilepsy (MTLE) on the global
characteristics of brain connectivity estimated by
topological measures. We used DSI (Diffusion Spectrum
Imaging) to construct a connectivity matrix where the
nodes represents the anatomical ROIs and the edges are
the connections between any pair of ROIs weighted by the
mean GFA/FA values. A significant difference was found
between the patient group vs control group in
characteristic path length, clustering coefficient and
small-worldness. This suggests that the MTLE network is
less efficient compared to the network of the control
group.
Keywords
MRI, DSI, Tractography, Epilepsy, Graph, LTS5
Create date
06/01/2014 22:07
Last modification date
20/08/2019 15:11
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