Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Role de la scintigraphie au DMSA dans la prise en charge des pyelonephrites de l'enfant. [Role of DMSA scintigraphy in managing pediatric pyelonephritis]
Archives de Pediatrie
5 Suppl 3
Pyelonephritis in children may lead to irreversible renal damage and eventually to arterial hypertension and renal insufficiency. Inflammation plays a central role in the pathogenesis of pyelonephritis. Dimercaptosuccinic acid (DMSA) scintigraphy permits detection of acute renal lesions and renal scars with high sensitivity and specificity. In our experience 60% of patients who had acute renal lesions on DMSA scintigraphy during pyelonephritis develop scars. Young age appears to be not a risk factor, as in our experience 70% of children older than 5 years develop scars compared to 40% for children younger than 1 year. In addition, only 40% of patients who develop scars have vesicoureteral reflux. DMSA scintigraphy may provide answers to important clinical questions: what is the optimal length of treatment of pyelonephritis? Is parenteral treatment necessary? What is the best treatment of vesicoureteral reflux? DMSA scintigraphy permits therapeutical decision-making according to the renal involvement in each of our patients.
Acute Disease Adolescent Child Child, Preschool Female Humans Infant Male Patient Care Planning Pyelonephritis/etiology/*radionuclide imaging Risk Factors Technetium Tc 99m Dimercaptosuccinic Acid/*diagnostic use
Last modification date