Ré-irradiation de compression médullaire sur foyer d’hématopoïèse extra médullaire : présentation d’un cas [Re-irradiation of bone marrow compression on a focus of extra medullary hematopoiesis: Presentation of a case]
Details
Serval ID
serval:BIB_5743992797E8
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Ré-irradiation de compression médullaire sur foyer d’hématopoïèse extra médullaire : présentation d’un cas [Re-irradiation of bone marrow compression on a focus of extra medullary hematopoiesis: Presentation of a case]
Journal
Cancer radiotherapie
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Publication state
Published
Issued date
04/2023
Peer-reviewed
Oui
Volume
27
Number
2
Pages
158-162
Language
french
Notes
Publication types: Case Reports ; English Abstract
Publication Status: ppublish
Publication Status: ppublish
Abstract
We present the case of a 40-year-old patient with β-Thalassemia major who underwent decompressive palliative radiotherapy on symptomatic intracanal extra medullary hematopoiesis on three occasions between 2016 and 2020. We delivered normo-fractionated radiotherapy at a dose of 10Gy in five fractions on vertebrae T4 to T10 and L3 to S2, 20Gy in ten fractions on vertebrae C7 to T11, and 12Gy in six fractions on vertebrae C7 to T9. The treatment was well tolerated with complete recovery of the symptomatology during the first two irradiations, and almost complete recovery after the 3rd irradiation.
Keywords
Humans, Adult, Bone Marrow, Re-Irradiation, Hematopoiesis, Radiation Oncology, Palliative Care, Beta-thalassemia, Beta-thalassémie, Compression médullaire, Extra medullary hematopoiesis, Hématopoïèse extra médullaire, Medullary compression, Radiotherapy, Radiothérapie
Pubmed
Web of science
Open Access
Yes
Create date
29/08/2022 9:40
Last modification date
17/11/2023 8:12
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