PPARdelta/beta: the lobbyist switching macrophage allegiance in favor of metabolism.
Details
Serval ID
serval:BIB_5738B7D42731
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Title
PPARdelta/beta: the lobbyist switching macrophage allegiance in favor of metabolism.
Journal
Cell Metabolism
ISSN
1932-7420 ([electronic])
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
7
Number
6
Pages
467-469
Language
english
Notes
type validé Bibliomics
Abstract
Macrophages, which belong to the immune system, are increasingly being recognized for their contribution to metabolic regulation. In two studies by Kang et al. (2008) and Odegaard et al. (2008) in this issue of Cell Metabolism, we learn that alternative activation (M2a) of resident macrophages in liver and adipose tissue depends highly on PPARdelta/beta activity, leading to improved fatty acid metabolism and insulin sensitivity.
Keywords
Insulin, Lipid Metabolism, Macrophages/metabolism, Macrophages/physiology, Metabolism, PPAR delta/physiology, PPAR-beta/physiology
Pubmed
Web of science
Open Access
Yes
Create date
06/04/2009 15:56
Last modification date
20/08/2019 14:11
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