Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]

Détails

ID Serval
serval:BIB_56FB6F49D00F
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Suivi thérapeutique des médicaments (I). Les principes [Principles of therapeutic drug monitoring]
Périodique
Revue Médicale Suisse
Auteur(s)
Widmer N., Csajka C., Werner D., Grouzmann E., Decosterd L.A., Eap C.B., Biollaz J., Buclin T.
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
4
Numéro
165
Pages
1644-1668
Langue
français
Résumé
Requesting a blood level measurement of a drug is part of the global approach known as "Therapeutic Drug Monitoring". Diverse situations require this monitoring approach, such as inadequate response to treatment or organ failure. Every drug however does not possess all the characteristics for a TDM program. The therapeutic range of a TDM drug has indeed to be narrow and its interindividual pharmacokinetic variability to be wide. As the development of new drugs is currently slowing down, the precise management of existing treatments certainly deserves progress, but needs however to be applied rationally, starting from a valid indication to blood sampling, and ending with a sound dosage adaptation decision.
Mots-clé
Anti-Bacterial Agents, Anti-Retroviral Agents, Anticonvulsants, Antineoplastic Agents, Antiparasitic Agents, Antitubercular Agents, Cardiovascular Agents, Dose-Response Relationship, Drug, Drug Monitoring, Humans, Immunosuppressive Agents, Pharmaceutical Preparations, Product Surveillance, Postmarketing, Psychotropic Drugs
Pubmed
Création de la notice
22/01/2009 10:13
Dernière modification de la notice
20/08/2019 14:11
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