Diagnosis and management of asymptomatic bacteriuria in kidney transplant recipients: a survey of current practice in Europe.
Details
Serval ID
serval:BIB_56C54325FA29
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Diagnosis and management of asymptomatic bacteriuria in kidney transplant recipients: a survey of current practice in Europe.
Journal
Nephrology, dialysis, transplantation
Working group(s)
European Renal Association-European Dialysis Transplant Association (ERA-EDTA) Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) working group and the European Study Group for Infections in Compromised Hosts (E, COLLABORATORS (IN ALPHABETICAL ORDER), European Renal Association-European Dialysis Transplant Association (ERA-EDTA) Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) working group and the European Study Group for Infections in Compromised Hosts (ESGICH) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
Contributor(s)
Adams B., Agnelli C., Ailioaie O., Akan H., Amrouche L., Andrés A., Anglicheau D., Arnouts P., Baas M., Balgradean C., Bammens B., Battaglia Y., Baudoux T., Berto I.M., Binet I., Bistrup C., Bonofiglio R., Bosmans J.L., Bouatou Y., Bouvier N., Braconnier P., Bredewold E., Broeders N., Brunet P., Buchler M., Budde K., Buron F., Burtey S., Buscaroli A., Büttner S., Byrne C., Caldara R., Cassuto E., Catalano C., Cavaille G., Corbel A., Couzi L., Crespo M., Daga S., Debelle F., Dedinska I., Devine P., Dickenmann M., Dratwa M., Drgona L., Durlik M., Egidi M.F., Errasti P., Etienne I., Fariñas M.C., Fehr T., Fernández-Ruiz M., Founta P., Fourtounas K., Frangou E., Frimat L., Furian L., Garjau M., Garrigue V., Gatault P., Geddes C., Gerlinger M.P., Gheuens E., Ghisdal L., Gibbs P., Giral M., Girerd S., Golshayan D., Gompou A., Grossi P.A., Guglielmetti G., Guirado L., Hadaya K., Hazzan M., Helbert M., Hellemans R., Heller K., Heemann U., Henckes M., Hernandez D., Hertig A., Hiesse C., Hilbrands L., Hilton R., Hirzel C., Horcajada J.P., Hougardy J.M., Huynh-Do U., Idrizi A., Ismaili K., Jiménez C., Jourde-Chiche N., Kamar N., Kaminski H., Kanter J., Karras A., Kemlin D., Kes P., Kianda M., Klinger M., Knight S., Koneth I., Krrashi A., Kuypers D., Langlois A.L., Lang P., Lauzurica R., Le Moine A., Lebeaux D., Legendre C., Lemy A., Len O., Liakopoulos V., Lichodziejewska-Niemierko M., Yague MBL, Lopau K., Madhoun P., Magott-Procelewska M., Malik S., Montero A.M., Marchini F., Marega A., Mariat C., Mark P., Martin P.Y., Martín L., Martín-Moreno P.L., Massart A., Matignon M., Maurel S., Mazuecos A., Melexopoulou C., Melilli E., Merino E., Mesic E., Messa P., Michalak M., Minetti E., Miserlis G., Montejo M., Moriconi D., Mottola C., Mourad G., Mueller T., Muñoz P., Nabokow A., Naesens M., Nikodimopoulou M., Oberbauer R., Olmedo M., Olsburgh J., Oniscu G., Øzbay L.A., Palmisano A., Papagianni A., Papasotiriou M., Parodi A., Parry R., Pascual J., Flores I.P., Pérez-Sáez M.J., Peruzzi L., Petit-Hoang C., Phelan P., Pillebout E., Piotti G., Pipeleers L., Pleros C., Popoola J., Pretagostini R., Psimenou E., Puig J., Rafat C., Bloudickova S.R., Bushljetikj I.R., Ratkovic M., Redondo D., Reischig T., Robert T., Ferrero MLR, Rroji M., Rutkowski P., Rydzewska-Rosolowska A., Sabé N., Sahali D., Salzberger B., San-Juan R., Sobrino B.S., Sandrini S., Santos L., Sava R., Schaub S., Schikowski J., Schvartz B., Sester U., Silva J.T., Snanoudj R., Somenzi D., Sørensen S., Rømming Sørensen V., Spanos G., Steiger J., Suwelack B., Theodoropoulou E., Thervet E., Thorban S., Tognarelli G., Tournay Y., Tricot L., Tulissi P., Vacher-Coponat H., Valerio M., Van Der Meijden WAG, Van Hamersvelt H., Van Laecke S., Vandivinit A., Vanholder R., Veroux M., Viklicky O., Vigo E., Viscoli C., Watschinger B., Weekers L., Welberry Smith M., Wissing K.M., Zeneli N., Zervos A., Zibar L., Zuber J., Zukunft B.
ISSN
1460-2385 (Electronic)
ISSN-L
0931-0509
Publication state
Published
Issued date
01/09/2018
Peer-reviewed
Oui
Volume
33
Number
9
Pages
1661-1668
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Asymptomatic bacteriuria is frequent in kidney transplant recipients (KTRs). However, there is no consensus on diagnosis or management. We conducted a European survey to explore current practice related to the diagnosis and management of asymptomatic bacteriuria in adult KTRs.
A panel of experts from the European Renal Association-European Dialysis Transplant Association/Developing Education Science and Care for Renal Transplantation in European States working group and the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases designed this cross-sectional, questionnaire-based, self-administered survey. Invitations to participate were e-mailed to European physicians involved in the care of KTRs.
Two hundred and forty-four participants from 138 institutions in 25 countries answered the survey (response rate 30%). Most participants [72% (176/244)] said they always screen for asymptomatic bacteriuria in KTRs. Six per cent (15/240) reported never treating asymptomatic bacteriuria with antibiotics. When antimicrobial treatment was used, 24% of the participants (53/224) said they would start with empirical antibiotics. For an episode of asymptomatic bacteriuria caused by a fully susceptible microorganism and despite no contraindications, a majority of participants (121/223) said they would use a fluoroquinolone (n = 56), amoxicillin/clavulanic acid (n = 38) or oral cephalosporins (n = 27).
Screening for and treating asymptomatic bacteriuria are common in KTRs despite uncertainties around the benefits and harms. In an era of antimicrobial resistance, further studies are needed to address the diagnosis and management of asymptomatic bacteriuria in these patients.
A panel of experts from the European Renal Association-European Dialysis Transplant Association/Developing Education Science and Care for Renal Transplantation in European States working group and the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases designed this cross-sectional, questionnaire-based, self-administered survey. Invitations to participate were e-mailed to European physicians involved in the care of KTRs.
Two hundred and forty-four participants from 138 institutions in 25 countries answered the survey (response rate 30%). Most participants [72% (176/244)] said they always screen for asymptomatic bacteriuria in KTRs. Six per cent (15/240) reported never treating asymptomatic bacteriuria with antibiotics. When antimicrobial treatment was used, 24% of the participants (53/224) said they would start with empirical antibiotics. For an episode of asymptomatic bacteriuria caused by a fully susceptible microorganism and despite no contraindications, a majority of participants (121/223) said they would use a fluoroquinolone (n = 56), amoxicillin/clavulanic acid (n = 38) or oral cephalosporins (n = 27).
Screening for and treating asymptomatic bacteriuria are common in KTRs despite uncertainties around the benefits and harms. In an era of antimicrobial resistance, further studies are needed to address the diagnosis and management of asymptomatic bacteriuria in these patients.
Keywords
Adult, Anti-Bacterial Agents/therapeutic use, Asymptomatic Infections/epidemiology, Asymptomatic Infections/therapy, Bacteriuria/diagnosis, Bacteriuria/drug therapy, Bacteriuria/microbiology, Cross-Sectional Studies, Europe/epidemiology, Female, Humans, Kidney Transplantation/adverse effects, Male, Practice Patterns, Physicians'/statistics & numerical data, Surveys and Questionnaires, Transplant Recipients
Pubmed
Web of science
Open Access
Yes
Create date
14/04/2018 10:14
Last modification date
04/10/2019 6:08
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