Indocyanine green angiographic features in tuberculous chorioretinitis

Details

Serval ID
serval:BIB_55045EF95FA2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Indocyanine green angiographic features in tuberculous chorioretinitis
Journal
American Journal of Ophthalmology
Author(s)
Wolfensberger  T. J., Piguet  B., Herbort  C. P.
ISSN
0002-9394 (Print)
Publication state
Published
Issued date
03/1999
Volume
127
Number
3
Pages
350-3
Notes
Journal Article --- Old month value: Mar
Abstract
PURPOSE: To determine choroidal involvement in presumed tuberculous posterior uveitis by examining indocyanine green angiographic features. METHODS: Indocyanine green angiography was performed according to a standard uveitis angiographic protocol in eight consecutive patients (15 eyes) with presumed posterior tuberculous uveitis. RESULTS: In 100% of the 15 examined eyes, indocyanine green angiography disclosed choroidal lesions that were subclinical, not detected by fundus examination or fluorescein angiography, in six (40%) of 15 eyes. Findings were classified into four main angiographic signs: (1) irregularly distributed, hypofluorescent areas in the early and intermediate phases of angiography that either became isofluorescent (type 1 hypofluorescence) or remained hypofluorescent (type 2 hypofluorescence) in the late phase; (2) numerous, small, focal, hyperfluorescent spots; (3) choroidal vessels that appeared fuzzy in the intermediate phase because of leakage, leading in the late phase to (4) diffuse choroidal hyperfluorescence. Type 1 hypofluorescent lesions, fuzzy choroidal vessels, and diffuse choroidal hyperfluorescence tended to regress after the initiation of antituberculous and corticosteroid treatment. Focal hyperfluorescence tended to be associated with longstanding disease. CONCLUSIONS: Indocyanine green angiography was useful in assessing and quantifying the as yet unknown extent of choroidal involvement in tuberculous posterior uveitis. Its characteristic appearance may be a valuable contribution to the diagnosis and monitoring of treatment response.
Keywords
Chorioretinitis/*diagnosis/*microbiology Choroid/blood supply Female *Fluorescein Angiography Fluorescent Dyes/*diagnostic use Fundus Oculi Humans Indocyanine Green/*diagnostic use Male Middle Aged Tuberculosis, Ocular/*diagnosis
Pubmed
Web of science
Create date
28/01/2008 13:05
Last modification date
20/08/2019 14:09
Usage data