Malignant metastasizing solitary fibrous tumors of the liver: a report of three cases.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_54A1F9253D70
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Malignant metastasizing solitary fibrous tumors of the liver: a report of three cases.
Journal
Polish journal of pathology : official journal of the Polish Society of Pathologists
Author(s)
Maccio L., Bonetti L.R., Siopis E., Palmiere C.
ISSN
1233-9687 (Print)
ISSN-L
1233-9687
Publication state
Published
Issued date
03/2015
Peer-reviewed
Oui
Volume
66
Number
1
Pages
72-76
Language
english
Notes
Publication types: Case Reports ; Journal Article

Abstract
Solitary fibrous tumors are rare neoplasms of mesenchymal origin that have been reported in various other extrathoracic sites, including the liver. We present a case series of three malignant solitary fibrous tumors of the liver, occurring in two women 74 and 80 years old and one 65-year-old man. No clinical features were predictive of malignancy except the large sizes and synchronous presence of lung metastases in two of the three cases. Histological examinations revealed the presence of high pleomorphic cellularity with nuclear atypia, necrosis and high mitotic ratios. All patients died of disease progression.

Keywords
Abdominal Neoplasms/chemistry, Abdominal Neoplasms/secondary, Abdominal Neoplasms/therapy, Aged, Aged, 80 and over, Biomarkers, Tumor/analysis, Biopsy, Disease Progression, Fatal Outcome, Female, Humans, Immunohistochemistry, Liver Neoplasms/chemistry, Liver Neoplasms/pathology, Liver Neoplasms/therapy, Lung Neoplasms/chemistry, Lung Neoplasms/secondary, Lung Neoplasms/therapy, Male, Mitosis, Necrosis, Solitary Fibrous Tumors/chemistry, Solitary Fibrous Tumors/secondary, Solitary Fibrous Tumors/therapy, Time Factors, Tomography, X-Ray Computed, Tumor Burden
Pubmed
Web of science
Open Access
Yes
Create date
02/06/2015 10:13
Last modification date
20/08/2019 15:09
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