[Progressive multifocal leukoencephalopathy in a non-AIDS patient: high efficiency of combined cytarabine and cidofovir]
Details
Serval ID
serval:BIB_548058C201BC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
[Progressive multifocal leukoencephalopathy in a non-AIDS patient: high efficiency of combined cytarabine and cidofovir]
Journal
Rev Med Interne
ISSN
0248-8663 (Print)
ISSN-L
0248-8663
Publication state
Published
Issued date
07/2007
Volume
28
Number
7
Pages
488-91
Language
english
Notes
Terrier, B
Hummel, A
Fakhouri, F
Jablonski, M
Hugle, T
Gasnault, J
Sanson, M
Martinez, F
fre
Case Reports
France
Rev Med Interne. 2007 Jul;28(7):488-91. doi: 10.1016/j.revmed.2007.05.013. Epub 2007 Jun 8.
Hummel, A
Fakhouri, F
Jablonski, M
Hugle, T
Gasnault, J
Sanson, M
Martinez, F
fre
Case Reports
France
Rev Med Interne. 2007 Jul;28(7):488-91. doi: 10.1016/j.revmed.2007.05.013. Epub 2007 Jun 8.
Abstract
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the central nervous system, occurring in immunocompromised patients. Treatment, not codified to date, is more often inefficient with a rapid and fatal deterioration. CASE RECORD: A 48-year-old woman, treated with immunosuppressant agents for systemic lupus, presented with PML mimicking neurolupus flare. A complete remission was obtained with cytarabine and cidofovir. CONCLUSION: Combined cytarabine and cidofovir appears a promising therapeutic option in PML associated with autoimmune systemic disorders.
Keywords
Antiviral Agents/*therapeutic use, Cidofovir, Cytarabine/*therapeutic use, Cytosine/*analogs & derivatives/therapeutic use, Drug Therapy, Combination, Female, Humans, Immunosuppressive Agents/*adverse effects, Leukoencephalopathy, Progressive Multifocal/*diagnosis/*drug therapy, Lupus Erythematosus, Systemic/drug therapy, Middle Aged, Opportunistic Infections/drug therapy/virology, Organophosphonates/*therapeutic use, Treatment Outcome
Pubmed
Create date
01/03/2022 10:18
Last modification date
02/03/2022 6:36
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